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  • Amiloride, Hydrochlorothiazide (Moduretic) 5 mg / 50 mg tablets
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    Moduretic (Amiloride Hydrochloride; Hydrochlorothiazide)Amiloride with Hydrochlorothiazide (trade names include Moduretic; Ameride; Amilorid Comp; Amiloride HCTZ; Amizide; Aquaretic; Co-Amilozide; Comilorid; Diurex A; Kaluril; Moduret; Moduretik; Normorix; Novamilor; Rhefluin) is a combined medication containing low-ceiling diuretic ("water pill") Hydrochlorothiazide from thiazides pharmacological group and potassium-sparing agent Amiloride. This medicine is used for treating high blood pressure (hypertension, HBP). It is also reduces the swelling and water retention caused by various medical conditions, such as heart, liver, or kidney disease. Hydrochlorothiazide works by making the kidneys eliminate sodium (salt) and water from the body, which helps to lower blood pressure and / or edema. Amiloride helps to minimize potassium loss. This medication may be used alone or with other drugs.

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    General information about Amiloride with Hydrochlorothiazide (Moduretic):


    Pharmacological and medical categories hydrochlorothiazide with amiloride:

  • Antihypertensive drugs
  • Potassium-sparing diuretics
  • Thiazide diuretics
  • Combined diuretics


    The Anatomical Therapeutic Chemical (ATC) classification system codes:

  • Essential (primary) hypertension - I10
  • Oedema, not elsewhere classified - R60


    Pregnancy categories Amiloride with Hydrochlorothiazide (Moduretic):

  • B - Australia
  • B - United States (No evidence of risk in humans)


    Salts and other forms used as active pharmaceutical ingredients (API):

  • Hydrochlorothiazide with Amiloride
  • Hydrochlorothiazide with Amiloride Hydrochloride
  • Hydrochlorothiazide with Amiloride Hydrochloride Anhydrous


    Synonyms, international and chemical names:

  • Amilorida
  • Amiloridum
  • Amipramidin
  • Amipramizid
  • Amipramizide
  • Amiprazidine
  • Guanamprazin
  • Guanamprazine

  • Dihydrochlorothiazid
  • Dihydrochlorothiazide
  • Dihydrochlorothiazidum
  • HCT
  • HCTZ
  • HCZ
  • Hidrochlortiazid
  • Hidroclorotiazida
  • Hidrohlorotiazid
  • Hidrohlortiazids
  • Hidroklorotiazid
  • Hydrochloorthiazide
  • Hydrochlorothiazid
  • Hydrochlorothiazidum
  • Hydrochlorotiazyd
  • Hydrochlorthiazide
  • Hydrochlorthiazidum
  • Hydroklooritiatsidi
  • Hydroklortiazid
  • HZT
  • Idroclorotiazide


    Brands, generics, trade names in various countries:

  • Adco-Retic - Adcock Ingram
  • Ameride - Bristol-Myers Squibb
  • Amiloferm - Nordic Drugs
  • Amiloretic - Pharmacare
  • Amiloretik - Hexal
  • Amilorid Comp - CT-Arzneimittel; Ratiopharm; Upsamedica
  • Amilorid HCT - Aliud Pharma; Helvepharm; Sandoz
  • Amiloride HCTZ - Helvepharm
  • Amiloride; Hydrochlorothiazide - Mylan; Sandoz; Teva; Watson Pharmaceuticals
  • Amilozid-B - Teva
  • Amizide - Merck; Alphapharm; Pacific Pharmaceuticals; Pinewood Laboratories; Sandoz
  • Apo-Amilzide - Apotex; Pharmaforte
  • Aquaretic - Sandoz; Azupharma
  • Biduret - GlaxoSmithKline
  • Comilorid - Mepha
  • Diurex - Orion Pharma
  • Diurex A - Bago Laboratorios
  • Ecodurex - Sandoz; Ecosol
  • Kaluril - Merck; Teva
  • Loradur - Ratiopharm
  • Lorinid Mite - Actavis
  • Milorex - Pharmadica
  • Moduret - Bristol-Myers Squibb; Merck; Prempharm; United Drug
  • Moduretic - Bristol-Myers Squibb; Merck
  • Moduretic Mite - Bristol-Myers Squibb; Merck
  • Moduretik - Bristol-Myers Squibb
  • Normorix - Nycomed
  • Novamilor - Novopharm
  • Rhefluin - Wyeth; Medika, Switzerland; Teva; Zentiva


    Pharmaceutical active ingredients used in medicine in combinations with amiloride and hydrochlorothiazide:

  • Atenolol
  • Methyldopa
  • Timolol Maleate


    Some other medications in the same pharmacological classes:

  • Adalat (Nifedipine)
  • Aldactazine (Altizide; Spironolactone)
  • Aldactone (Spironolactone)
  • Aldazide (Butizide; Spironolactone)
  • Aldoleo (Chlorthalidone; Spironolactone)
  • Altace (Ramipril)
  • Avalide (Irbesartan; Hydrochlorothiazide)
  • Benicar (Olmesartan)
  • Benicar HCT (Olmesartan; Hydrochlorothiazide)
  • Bystolic (Nebivolol)
  • Cardura (Doxazosin)
  • Diovan (Valsartan)
  • Diovan HCT (Valsartan; Hydrochlorothiazide)
  • Dyta-Urese (Epitizide; Triamterene)
  • Esmalorid (Trichlormethiazide; Amiloride Hydrochloride)
  • Frumil (Amiloride; Furosemide)
  • Hytrin (Terazosin)
  • Hyzaar (Losartan; Hydrochlorothiazide)
  • Inderal (Propranolol)
  • Lasix (Furosemide)
  • Micardis (Telmisartan)
  • Micardis HCT (Telmisartan; Hydrochlorothiazide)
  • Microzide (Hydrochlorothiazide)
  • Norvasc (Amlodipine)
  • Saluretin (Bendroflumethiazide; Spironolactone)
  • Serpasil-Navidrex-K (Cyclopenthiazide; Potassium Chloride; Reserpine)
  • Tenoretic (Atenolol; Chlorthalidone)
  • Tenormin (Atenolol)
  • Triniagar (Mebutizide; Triamterene)
  • Vaseretic (Enalapril; Hydrochlorothiazide)
  • Zebeta (Bisoprolol)
  • Zestoretic (Lisinopril; Hydrochlorothiazide)
  • Ziac (Bisoprolol; Hydrochlorothiazide)


    Here is a list of popular medications containing Amiloride" and "Hydrochlorothiazide" as main components of hydrochlorothiazide with amiloride drugs, their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Ameride
  • N / A
  • Bristol-Myers Squibb
  • Amilorid Comp
  • Tablets; Oral; Amiloride Hydrochloride; Hydrochlorothiazide
  • Ratiopharm
  • Amiloride; Hydrochlorothiazide
  • Tablets; Oral; Amiloride Hydrochloride 5 mg; Hydrochlorothiazide 50 mg
  • Sandoz
  • Amizide
  • Tablets; Oral; Amiloride Hydrochloride 5 mg; Hydrochlorothiazide 50 mg
  • Merck
  • Alphapharm
  • Pacific Pharmaceuticals
  • Pinewood Laboratories
  • Sandoz
  • Aquaretic
  • Tablets; Oral; Amiloride Hydrochloride; Hydrochlorothiazide
  • Sandoz
  • Azupharma
  • Comilorid
  • Tablets; Oral; Amiloride Hydrochloride 5 mg; Hydrochlorothiazide 50 mg
  • Mepha
  • Kaluril
  • Tablets; Oral; Amiloride Hydrochloride 5 mg; Hydrochlorothiazide 50 mg
  • Merck
  • Teva
  • Moduret
  • Tablets; Oral; Amiloride Hydrochloride 2.5 mg; Hydrochlorothiazide 25 mg
  • Tablets; Oral; Amiloride Hydrochloride 5 mg; Hydrochlorothiazide 50 mg
  • Bristol-Myers Squibb
  • Merck
  • Prempharm
  • United Drug
  • Moduretic
  • Tablets; Oral; Amiloride Hydrochloride 2.5 mg; Hydrochlorothiazide 25 mg
  • Tablets; Oral; Amiloride Hydrochloride 5 mg; Hydrochlorothiazide 50 mg
  • Bristol-Myers Squibb
  • Aspen
  • BLH Trading
  • DKSH
  • Four Star
  • M & H Manufacturing
  • Merck
  • United Drug
  • Vianex
  • Zuellig Pharma
  • Moduretik
  • Tablets; Oral; Amiloride Hydrochloride 2.5 mg; Hydrochlorothiazide 25 mg
  • Tablets; Oral; Amiloride Hydrochloride 5 mg; Hydrochlorothiazide 50 mg
  • Bristol-Myers Squibb
  • Novamilor
  • Tablets; Oral; Amiloride Hydrochloride 5 mg; Hydrochlorothiazide 50 mg
  • Novopharm
  • Rhefluin
  • Tablets; Oral; Amiloride Hydrochloride 2.5 mg; Hydrochlorothiazide 25 mg
  • Tablets; Oral; Amiloride Hydrochloride 5 mg; Hydrochlorothiazide 50 mg
  • Wyeth
  • Medika, Switzerland
  • Teva
  • Zentiva



  • References:

  • PubChem database with main scientific information about active pharmaceutical ingredients : https://pubchem.ncbi.nlm.nih.gov/
  • PubMed database on US National Library of Medicine, National Institutes of Health: https://www.ncbi.nlm.nih.gov/pubmed/
  • DrugBank database containing information on drugs and drug targets: https://www.drugbank.ca/
  • MedlinePlus - an online information service produced by the United States National Library of Medicine: https://medlineplus.gov/
  • WebMD - an online publisher of news and information pertaining to human health and well-being: https://www.webmd.com/
  • Medscape - a website providing access to medical information for physicians and health professionals: https://www.medscape.com/
  • DailyMed drug labels resource from U.S. National Library of Medicine: https://dailymed.nlm.nih.gov/dailymed/spl-resources-all-drug-labels.cfm
  • Mayo Clinic - a nonprofit academic medical center focused on integrated clinical practice, education, and research: https://www.mayoclinic.org/
  • Drugs@FDA: U.S. Food and Drug Administration approved drug products database: https://www.accessdata.fda.gov/scripts/cder/daf/
  • Drug Product Database online query from Health Canada: https://health-products.canada.ca/dpd-bdpp/index-eng.jsp
  • European Medicines Agency (EMA) website with "Search for medicines" tool for European Union countries: https://www.ema.europa.eu/en
  • UK drug database from electronic Medicines Compendium (eMC): https://www.medicines.org.uk/emc
  • Australian medicine finder from NPS MedicineWise: https://www.nps.org.au/medicine-finder
  • Agencia Espanola de Medicamentos y Productos Sanitarios - AEMPS: https://www.aemps.gob.es/
  • Pharma and medical DB in EU on CBG-MEB: https://www.cbg-meb.nl/
  • Huge database for drug search especially for european and Latin America region: https://www.vademecum.es/equivalencia
  • MyHealthbox - multilanguage search engine for official information on medicines and healthcare products: https://myhealthbox.eu/en/
  • Pharmaceutical and other healthcare databases in some countries, primarily across Asia Pacific: https://www.mims.com/
  • MIMS drug index in China: http://www.mims.com.cn/china/drug/index/
  • IndiaMart - Various exploring tools, including for medical and pharmaceutical products in India: https://dir.indiamart.com/
  • A to Z brands and generics with their comparative prices on MedGuideIndia: http://www.medguideindia.com/show_generics.php
  • Generic drugs with their brand names on Medindia: https://www.medindia.net/drug-price/index.asp
  • Online Drug Information System, primarily for India and Pakistan: http://www.druginfosys.com/
  • Medizzine - hispanic portal for medicines: http://www.medizzine.com/pacientes/medicamentos/index.php
  • English version of Medizzine - health & medicines portal: http://www.medizzine.com/en/patients/drugs/index.php
  • Search tools for medications on Japanese Orange Book: http://www.jp-orangebook.gr.jp/cgi-bin/search/search_e.cgi
  • South Korean PharmaLink gateway: http://www.pharmalink.kr/
  • Medicines brand and generic index for Africa region: https://daktariafrica.com/medicine/raw/index/
  • APIs database on Galinos: https://www.galinos.gr/web/drugs/main/substances
  • RLSNet index for drugs, nutritions and supplements in Russia, Eastern Europe and Middle Asia regions: https://www.rlsnet.ru/tn_alf.htm
  • Taiwan Food and Drug Administration: https://www.fda.gov.tw/TC/index.aspx
  • Online medicine information directory from MedEx: https://medex.com.bd/generics/
  • The Anatomical Therapeutic Chemical ATC/DDD Index 2019: https://www.whocc.no/atc_ddd_index/
  • International Statistical Classification of Diseases and Related Health Problems 10th Revision, WHO: https://www.icd10data.com/

    Updated: September, 2019



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